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Dermatology

By Guy F. Webster, Anthony V. Rawlings

ISBN-10: 0824729714

ISBN-13: 9780824729714

Addressing some of the most more often than not encountered stipulations obvious by way of the dermatologist, this resource analyzes the pathophysiology, overview, analysis, scientific good points, and keep watch over of pimples. With full-color illustrations, this resource delves into the on hand treatments for tough instances of zits and scarring and gives specialist discussions of administration regimens together with topical and systemic remedies, laser remedies, and new medicinal drugs.

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66. Philpott MP, Sanders DA, Kealey T. Is the sebaceous gland important for inner root sheath breakdown? In: Van Neste D, Randall VA, eds. Hair Research for the Next Milennium. Amsterdam: Elsevier, 1996:393– 395. 67. Gates AH, Karasek M. Hereditary absence of sebaceous glands in mouse. Science 1965; 148:1471– 1473. 68. Downing DT, Stewart ME, Strauss JS. Changes in sebum secretion and the sebaceous gland. Clin Geriatr Med 1989; 5(1):109– 114. 69. Kligman AM. The uses of sebum. Br J Dermatol 1963; 75:307– 319.

Pierard-Franchimont C, Pierard GE. Postmenopausal aging of the sebaceous follicle: a comparison between women receiving hormone replacement therapy or not. Dermatology 2003; 204(1):17– 22. 61. Zouboulis CC, Boschnakow A. Chronological ageing and photoageing of the human sebaceous gland. Clin Exp Dermatol 2001; 26(7):600– 607. 62. Thiele JJ, Weber SU, Packer L. Sebaceous gland secretion is a major physiologic route of vitamin E delivery to skin. J Invest Dermatol 1998; 113:390– 395. 63. Fluhr JW, Man M-Q, Brown BE, et al.

DK4962-Webster-ch2_R2_240307 Cell Biology of the Pilosebaceous Unit 21 FIGURE 4 Immunohistochemical labeling of a cross-section through the infundibulum of a sebaceous follicle stained with a monoclonal antibody for androgen receptors. Positively stained nuclei are dark gray. to relate the rate of sebum production to differences in androgen receptor levels in different acne patients. Androgen receptor antagonists, such as oral cyproterone acetate and spironolactone compete with androgens for the androgen receptor-binding site (101), and while both compounds effectively decrease sebum production, they also have feminizing side-effects.

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Acne and its therapy by Guy F. Webster, Anthony V. Rawlings


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