Download e-book for kindle: AIDS Epidemiology: A Quantitative Approach (Monographs in by Ron Brookmeyer (Author), Mitchell H. Gail (Author)
By Ron Brookmeyer (Author), Mitchell H. Gail (Author)
AIDS has seemed in additional than a hundred thirty nations, and over 100,000 situations of AIDS were suggested within the U.S. on my own. an increasing number of, the general public may be reckoning on statisticians to supply solutions concerning the destiny process this epidemic. This finished paintings confronts the issues which are targeted to AIDS learn and unites them below a unmarried conceptual framework. It specializes in equipment for the layout and research of epidemiologic reports, the usual historical past of AIDS and the transmission of HIV, tools for monitoring and projecting the process the epidemic, and statistical matters in healing trials. many of the equipment of tracking and forecasting this illness obtain finished remedy. those tools comprise back-calculation, which the authors constructed; interpretation of survey info on HIV occurrence; mathematical types for HIV transmission; and ways that mix types of epidemiological info. a lot of this fabric -- resembling a dialogue of tools for assessing security of the blood provide, an overview of survey techniques, and strategies to venture pediatric AIDS prevalence -- isn't to be had in the other paintings.
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Additional resources for AIDS Epidemiology: A Quantitative Approach (Monographs in Epidemiology and Biostatistics ; V. 22)
In these case-control and cohort studies, there is usually 19 20 AIDS Epidemiology: A Quantitative Approach little information on the precise time or times when exposure to HIV occurred. For example, an individual may have no idea whether or not a given sexual partner is infected. However, in other types of studies, the date or dates of exposure to HIV are more precisely defined. For example, a hospital worker will often know the precise date on which he or she may have been inadvertently stuck by a contaminated needle, and recipients of blood transfusions that are later found to have been contaminated can be studied to determine what proportion of the recipients became seropositive.
Pattern I refers to areas where HIV began to spread in the late 1970s principally among homosexual and bisexual men and intravenous drug users. North American, Western Europe, and parts of Latin America have been described as Pattern I. Pattern II refers to areas where HIV began to spread in the 1970s principally among heterosexuals and where the ratio of infected males to females is approximately 1:1. Sub-Saharan Africa and parts of the Caribbean 18 AIDS Epidemiology: A Quantitative Approach have been described as Pattern II.
An important factor that affects this probability is the number of sexual contacts between the index case and the susceptible partner that occur subsequent to the infection of the index case. Additional factors that could affect the transmission probability include type of sexual behavior, use of condoms, degree of immunosuppression of the index case and presence of other sexually transmitted diseases or conditions such as genital ulceration. Ideally, a partner study would be conducted prospectively.
AIDS Epidemiology: A Quantitative Approach (Monographs in Epidemiology and Biostatistics ; V. 22) by Ron Brookmeyer (Author), Mitchell H. Gail (Author)